AWAKEN increases neuroplasticity by increasing levels of two key peptides, BDNF and NGF. This encourages the growth of new neurons and makes it easier for new neural connections to form, increasing fluid intelligence and accelerating the speed with which you can learn new information and skills.
AWAKEN increases levels of the key neurotransmitters associated with both long-term and short-term memory, improving your ability to create and recall memories.
Enhance Focus & Clarity
AWAKEN increases the levels of key neurotransmitters that enhance your ability to focus and think clearly. AWAKEN also helps to reduce stress and anxiety, which make focusing and thinking clearly more difficult.
AWAKEN increases levels of key neurotransmitters associated with positive thinking, motivation and drive, so you can start your day with the right mindset to succeed at whatever you pursue.
PEA is naturally produced by the human body and is a "neuro-amplifier", which has unique and rapid uplifting effects on mood, attention, motivation, alertness, creativity, awareness and sensory perceptions.
PEA supplementation provides rapid improvements to mental clarity, mood and motivation. PEA functions as both a neurotransmitter, improving focus, attention, goal-directed behavior and task-completion and increases the actions of Dopamine (for motivation and drive), Norepinephrine (for wakefulness and higher performance), Acetylcholine (for improved memory and neural activity), and Serotonin (for improved mood and impulse control).
The Many Health Benefits of Phenylethylamine (PEA) - Your Brain’s Natural Stimulant
Phenylethylamine, a small molecule with a large impact
PQQ supplementation has been shown to optimize the health and function of the entire central nervous system, improving energy levels, memory and higher cognitive function. PQQ stimulates the growth of fresh mitochondria (the organelles that generate the energy that powers your brain and body). Mitochondria are the batteries that supply power to your body. As we age, the number of mitochondria we have in our cells decrease, reducing health and longevity. PQQ enhances the formation of new Mitochondria, increasing cellular energy production.
PQQ reverses aspects of cellular aging by protecting mitochondria (the powerhouses of your cells) from oxidative damage and activating genes that induce the growth of fresh mitochondria. A double-blind, placebo-controlled human clinical trial found that PQQ improved short-term memory, attention/concentration, information identification, and processing ability in healthy adults. Mitochondrial health is critical to cognitive function, because Acetylcholine, a key neurotransmitter that is essential to learning and memory formation, is primarily synthesized in the mitochondria and nerve cells in the brain require especially high numbers of healthy mitochondria to power the brain's massive energy needs. PQQ is also a neuroprotective and cardioprotective compound.
Generate Fresh Mitochondria with PQQ
Potential Physiological Important of PQQ
Pyrroloquinoline Quinone (PQQ) Prevents Cognitive Deficit Caused by Oxidative Stress in Rats
L-Theanine is a naturally occurring amino acid that reduces stress levels, promotes relaxation, boosts mood, and increases mental attention, alertness and cognition. It helps to provide a streamlined focus throughout the day.
L-Theanine has been shown in double-blind, placebo-controlled human trials to reduce stress levels, promote relaxation, boost mood, increase mental attention, alertness and cognition, increase alpha wave activity in the brain (which is associated with relaxed mental states) and increase theta wave activity in the brain (which is associated with improved learning and memory). L-Theanine increases GABA, Serotonin and Dopamine levels in the brain, as well as boosting Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF), which encourage the growth of new neurons and synapses and the repair of existing neurons, synapses and myelin, increasing neuroplasticity and learning. L-Theanine is also an antagonist of NMDA receptors which inhibits the release of glutamate, protecting your brain from over-stimulation.
L-Theanine Supplements - Brain Boosting and Mood Enhancing Effects
L-Theanine reduces psychological and physiological stress response
L-Theanine, a natural constituent in tea, and its effect on mental state
The deployment of intersensory selective attention: a high-density electrical mapping study of the effects of theanine
N-Acetyl L-Tyrosine is beneficial for improving cognition, focus, concentration, attention, and reducing stress. N-Acetyl L-Tyrosine is potent and bioavailable form of the amino acid L-Tyrosine. L-Tyrosine is key precursor to a number of neurotransmitters (including Dopamine, Norepinephrine and Epinephrine) and to Coenzyme Q10 (which is critical for mitochondrial health) and is critical to a number of bodily functions, including cognitive processes, building muscles and cell growth and recovery.
N-Acetyl L-Tyrosine has been shown in double-blind human trials to support peak performance by reducing stress, supporting positive mood and motivation and promoting focus and mental clarity. A number of studies have found that L-Tyrosine supplementation may improve mental performance under conditions of not only stress but also cold, fatigue, prolonged work, and even sleep deprivation.
L-Tyrosine: Benefits, Side Effects and Dosages Guide
Tyrosine improves cognitive performance and reduces blood pressure
The effects of tyrosine on cognitive performance during extended wakefulness
Treatment with Tyrosine, a neurotransmitter precursor, reduces environmental stress in humans
Tyrosine reverses a cold-induced working memory deficit in humans
KSM-66 (Ashwagandha Extract)
Ashwagandha promotes physical and mental health by reducing stress and anxiety, increasing neuroplasticity, improving cognitive and brain function, improving learning, memory and reaction time, enhancing immune system functions, and maintaining healthy lipid and glucose metabolism. KSM-66 is a patented Ashwagandha extract, offering the highest concentration full-spectrum root extract on the market today (more than 5% withanolides), retaining all the natural constituents of the herb in the original balance. It is produced using a first-of-its-kind extraction process, based on “Green-Chemistry” principles, without using alcohol or any other chemical solvents.
Ashwagandha translates as the “Smell of a Horse” indicating that the herb confers the strength of a stallion. Ashwagandha is a powerful Ayurvedic herb that promotes physical and mental health by reducing stress and anxiety, boosting levels of BDNF, regenerating axons and dendrites, reconstructing synapses, increasing myelin levels in the nervous system, improving cognitive and brain function, improving learning, memory and reaction time, enhancing immune system functions, and maintaining healthy lipid and glucose metabolism. Research from the Asha Hospital in Hyderabad found, in a study of 64 people with chronic stress, that Ashwagandha supplementation for two months decreased stress by 44% and decreased depression and/or anxiety by 72%.
Ashwagandha - A Natural Stress-Buster with Energy and Mood Benefits
Efficacy and Safety of Ashwagandha Root Extract in Improving Memory and Cognitive Functions
Efficacy and Safety of Ashwagandha Root Extract in Improving Memory and Cognitive Functions
Clinical Study Ashwagandha Effective in Reducing Stress and Anxiety
CDP Choline (Citicoline)
CDP Choline (Citicoline) is a precursor to the neurotransmitter Acetylcholine and enhances memory, improves focus and clarity, and increases mental energy. CDP Choline (Citicoline) is both highly bioavailable and easily crosses the blood-brain barrier, unlike many cheaper choline supplements, such as choline bitartrate. Nearly 90% of the population does not get sufficient choline from their diets, which can lead to mental impairment and deficiencies. Acetylcholine levels also decline as we age and rapidly decline after age 45. A high-quality choline nootropic is an essential component of any quality nootropic stack. CDP Choline (Citicoline) is the best choline nootropic for improving brain function and mental performance.
CDP Choline (Citicoline) has been shown in double-blind human trials to enhance memory, heighten focus, and increase mental energy and clarity. CDP Choline (Citicoline) metabolizes into both Choline and Uridine (which increases neuroplasticity, memory formation and boosts mood), making it the most effective Choline supplement for cognitive enhancement. CDP Choline (Citicoline) significantly increases the rate of choline synthesis (increasing levels of Acetylcholine in the brain), replenishes depleted levels of phospholipids and works synergistically with other nootropics to powerfully potentiate their effects. CDP Choline (Citicoline) (through Uridine) increases Dopamine receptor densities and encourages Dopamine release.
Citicoline: pharmacological and clinical review
CDP-choline as a biological supplement during neurorecovery: a focused review
Effect of CDP-choline on learning and memory processes in rodents
Dietary CDP Choline supplementation protects against development of memory deficits in aging rats
CDP Choline Increases Dopamine Receptor Density
CDP Choline Provides Neuroprotection for Dopaminergic Neurons
Uridine supplementation has been shown to increase neuroplasticity, improve working memory and fluid intelligence, and repair and increase the density of Dopamine receptors, reversing damage done by poor diet, lifestyle and other factors. Uridine 5'-Monophosphate is a highly bioavailable form of Uridine that easily crosses the blood-brain barrier (unlike Uridine derived from dietary sources).
Uridine supplementation enhances the growth of neurites, increasing neuroplasticity and facilitating improved learning and memory. Uridine helps to repair and improve the Dopamine system, by facilitating the repair of Dopamine receptors and increasing Dopamine receptor density, while also boosting the release of Dopamine, improving mood, motivation, focus, alertness and cognition. Uridine plays an important role in the synthesis of Acetylcholine (a neurotransmitter associated with learning and memory) and Phosphatidylcholine (a critical component of the phospholipid layer encasing neurons). Uridine 5'-Monophosphate is particularly effective when, as in AWAKEN, it is combined with CDP Choline (Citicoline) and Methylcobalamin (B12).
Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats.
Restorative Effects of Uridine Plus DHA
Synapse Formation and Cognitive Brain Development
Uridine Promotes Brain Plasticity
Phosphatidylserine supplementation significantly increases memory recognition, memory recall, executive functions and mental flexibility. Following supplementation total learning and immediate recall improve significantly. Phosphatidylserine is a phospholipid that contains both amino acids and fatty acids and is essential for healthy nerve cell membranes and myelin.
Phosphatidylserine supports positive mood, improves cognitive function and athletic performance by increasing aerobic endurance. Phosphatidylserine helps maintain brain cell membrane fluidity, helps optimize neuroreceptors, boosts Acetylcholine and Dopamine levels and serves as a phosphatidyl donor for phosphatidylcholine synthesis, when combined with CDP Choline (Citicoline).
What is Phosphatidylserine and what are its Brain Benefits?
The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
Phosphatidylserine Improves Memory Function
Effects of Phosphatidylserine in Alzheimer’s disease
An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline.
Methylcobalamin is a highly bioavailable form of Vitamin B12, which promotes healthy levels of energy production, maintains brain health, vitality, and enhanced mood. Vitamin B12 is involved in the metabolism of every cell in the human body, is a cofactor in the synthesis of Dopamine, GABA, Norepinephrine and Serotonin, and plays a key role in the generation and function of myelin.
Bioperine is an extract from black pepper, which has been shown to enhance the bioavailability and absorption of the other ingredients in AWAKEN. Early research also suggests that Bioperine may have some antidepressant capabilities as well.
Frequently Asked Questions
How many capsules should I take?
It will vary from individual to individual. We recommend that you start with 2 capsules in the morning. More advanced users may want to take 1 additional capsule in either the morning or in the early afternoon for an afternoon boost.
When should I take AWAKEN?
AWAKEN can be taken at any time and can be taken more than once per day (but you should limit yourself to a maximum of 4 capsules per day). We recommend taking AWAKEN each morning to start your day with your best foot forward. We recommend taking AWAKEN on an empty stomach in order to expedite absorption, but AWAKEN is also effective if taken with food and some people may find that preferable. We also recommend taking 1-2 capsules of AWAKEN about 30 minutes prior to whenever you want to kick your performance into higher gear – prior to an important meeting, a pitch, getting started on an important project, playing sports, practicing or performing, studying, taking an exam, etc.
When will I begin to feel the effects?
Most people begin to notice some of the effects after the first few times they take AWAKEN. The effects build over time and become considerably more pronounced after several weeks of daily use.
Can I drink coffee and/or tea with AWAKEN?
Absolutely! Caffeine works synergistically with AWAKEN and will amplify some of the effects. In addition to caffeine, taking DHA/Omega-3 Fish Oils with AWAKEN is highly synergistic. If you currently take caffeine, we recommend that you continue to do so, otherwise the symptoms of caffeine withdrawal may temporarily overpower the positive effects of AWAKEN. A minority of users may find the calming/anti-stress effects of AWAKEN to be especially potent and for those users we recommend taking AWAKEN with a cup of coffee.
If caffeine amplifies the effects why is it not included in AWAKEN?
Caffeine works synergistically with some components of AWAKEN, however caffeine is addictive and we wanted to leave the decision of whether or not to take caffeine up to you. Caffeine is also a vasoconstrictor and can put a lot of stress on the heart and cardiovascular system. As with all Awakened Alchemy product, we formulated AWAKEN to be purely healthy and side effect free.
Is AWAKEN a stimulant?
AWAKEN has mild stimulatory effects. These effects result from endogenous compounds and AWAKEN is therefore not considered a stimulant. Unlike caffeine and many other stimulants, you will not experience jitteriness or an energy level crash with AWAKEN. In fact, you will experience sustained elevated energy levels due to improved energy metabolism at the cellular level.
Is AWAKEN addictive?
No. We have carefully formulated AWAKEN to avoid all addictive substances. You will not build a tolerance to AWAKEN and there is no need to cycle off. Some users may prefer to cycle 4 weeks on/1 week off, or 5 days on/2 days off.
Do you use Magnesium Stearate?
No. Due to health concerns associated with the use of Magnesium Stearate, all Awakened Alchemy products use Nu-FLOW®, an organic flow agent made from sterilized rice hulls.
Are any animal products used in AWAKEN?
The current batch of Awaken is not vegan. In the making of KSM-66 Ashwagandha Extract, the roots are soaked in milk. We use the vegan version of KSM-66 in Awaken Gold, but the current batch of Awaken is made using the standard KSM-66.
Is AWAKEN safe for children and/or pregnant/breastfeeding women?
AWAKEN is intended for healthy adults aged 18 and over who are not pregnant. The ingredients used in AWAKEN are all considered to be very safe for healthy adults, however, there has been insufficient clinical research for us to conclude that they are also safe for children and/or pregnant/breastfeeding women.
I am amine intolerant, should I take AWAKEN?
AWAKEN contains phenylethylamine, a naturally occurring monoamine alkaloid better known as the "love molecule" found in cacao. Therefore, it you are amine intolerant, you should not take AWAKEN. Symptoms of amine intolerance may include headaches, nausea, hives, fatigue, digestive issues and/or vomiting.
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