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AGING AND NAD+

NMN is a revolutionary advance in anti-aging. By boosting NAD+, NMN can literally turn back the clock on age-associated physiological decline. It is one of six powerful anti-aging ingredients in THRIVE GOLD, which is designed to change the way you age and help you to live vibrantly, longer. Read more about why NMN is the most effective supplement to boost NAD+ here.

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme that is found in all living cells and is essential for many fundamental biological processes. NAD+ functions as a biological clock for age-associated gene expression. 

Low levels of NAD+ are associated with accelerated aging, fatigue, weight gain and other metabolic issues, cardiovascular disease, impaired brain function, impaired immune function and increased inflammation. 

The human body is designed to break down, die and make way for future generations. As the body ages, different genes are expressed and the deterioration of physical capacity, endurance and metabolism gradually occurs. 

One of the key ways the body regulates age-associated gene expression is through the ratio of NAD+ to NADH. NAD+ levels decline naturally as we age, whereas NADH levels remain relatively constant. Therefore the ratio of NAD+ to NADH approximates age and determines age-associated gene expression. 

By increasing levels of NAD+ above your baseline, effectively, you are manipulating the ratio of NAD+ to NADH and tricking your body into expressing the genes of a younger person. 

NAD+ activates a class of seven genes (and their associated enzymes) called Sirtuins, which are master regulatory genes. Sirtuins turn off expression of certain genes that promote aging, including genes involved in the regulation of inflammation, fat synthesis and storage and insulin-level management. 

With respect to aging in particular, NAD+ activates Sirtuins 1 and 3 (Sirt1 and Sirt3):

Sirt1, when activated by NAD+, activates genes:

  • PGC-1alpha, which stimulates mitochondrial biogenesis (growth of new mitochondria);
  • FOXO1, which reduces production of new fat cells;
  • P53, an anti-cancer gene that prevents cells with damaged DNA from growing into tumors; and
  • SREBP1c, which regulates blood sugar, fatty acid and fat production in response to insulin and controls cholesterol levels.

Sirt3, when activated by NAD+, activates genes:

  • SOD2, a mitochondrial antioxidant; and
  • LCAD, SDH and AceCS2, which are mitochondrial enzymes responsible for breaking down fatty acids and carbohydrates for ATP-generation (cellular energy generation).

NAD+ is also critical to PARP (Poly (ADP-ribose) polymerase) activity. PARP is an enzyme that repairs damaged DNA. The level of PARP activity determines the maximum lifespan of both mammalian species and individuals. Humans have significantly higher levels of PARP activity than shorter lived mammals and long-lived individuals have higher levels of PARP activity. Increasing PARP activity through increased NAD+ is expected to increase lifespan.

Add THRIVE GOLD to your daily regimen today and change the way you live and age.

NMN vs. NR: The Best Way to Increase NAD+ and Slow Aging

There are several widely marketed products that feature Nicotinamide Riboside (NR/Niagen) to increase NAD+ levels, which begs the question, which supplement is more effective for boosting NAD+, NMN or NR?

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AGING AND NAD+

NMN is a revolutionary advance in anti-aging. By boosting NAD+, NMN can literally turn back the clock on age-associated physiological decline. It is one of six powerful anti-aging ingredients in THRIVE, which is designed to change the way you age and help you to live vibrantly, longer. 

Read More ›

Nourish Your Brain For Peak Performance

Your mind is like a garden. The quality of the soils you plant your thoughts into determines how they grow and creates the person you will become, the goals you will achieve and the life you will experience. AWAKEN GOLD is a tool in the cultivation of your mind and acts like fertilizer to supercharge your neuroplasticity and increase your ability to learn, grow and develop your mind.

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Mitochondrial Health & Aging

The mitochondrial theory of aging proposes that accumulated damage to mitochondria, and their especially vulnerable DNA, leads to aging.

THRIVE was formulated to specifically focus on activation of anti-aging genes (sirtuins) and to improve mitochondrial health and function. It’s ingredients are explained below:

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Ingredient Quality and Quantity

At Awakened Alchemy we are committed to creating the highest quality nutritional products, based on principles of integrity, effectiveness and transparency. Our focus on rigorous scientific research-backed evidence-based formulations, use of only the highest quality ingredients, and gold-standard cGMP-certified domestic manufacturing, result in our supplements producing beneficial effects that greatly outperform other products.

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Smart Drugs Vs. Nutrition: Which Approach to Nootropics Is Right For You?

At Awakened Alchemy, we utilize high quality nutritional formulations to support and enhance the brain’s existing chemistry. By providing the brain with optimal nutrition, the brain grows healthier and stronger, resulting in significant improvements in cognitive function, learning ability, memory, focus, clarity, concentration, motivation and drive. The effects of improved brain nutrition compound over time resulting in dramatic improvements in function, performance and long-term brain health. 

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Creating Your Reality - Part 1

In Alchemy, the mind is understood to be the bridge between our awareness and external material world we perceive and experience. To the alchemist, the experience of reality is understood to be a creation of the mind and therefore, by changing our mind, we can change our reality.

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